Cajun Chicken Alfredo Orzo

Featured in: Spicy Entrées

This hearty dish blends tender chicken pieces with smoky Cajun seasoning, combined with velvety Alfredo sauce and tender orzo pasta. Cooked in a single pot, it offers a rich, comforting flavor profile enhanced by garlic, bell pepper, and Parmesan cheese. The creamy sauce balances spice and savoriness, making it ideal for quick weeknight dinners. Fresh spinach and parsley add brightness, while the dish’s simplicity allows for easy variations like shrimp or smoked sausage.

Updated on Sun, 23 Nov 2025 11:28:00 GMT
One-Pot Cajun Chicken Alfredo Orzo, a creamy, flavorful dish; the pasta and chicken blend deliciously. Save
One-Pot Cajun Chicken Alfredo Orzo, a creamy, flavorful dish; the pasta and chicken blend deliciously. | pepperplume.com

A creamy, spicy, and comforting one-pot meal combining tender chicken, smoky Cajun spices, velvety Alfredo sauce, and orzo pasta for a quick weeknight dinner.

I first prepared this recipe on a busy weeknight and loved how all the flavors melded together effortlessly in one pot.

Ingredients

  • Proteins: 2 large boneless skinless chicken breasts (about 450 g) cut into bite sized pieces
  • Vegetables: 1 small yellow onion finely chopped 3 cloves garlic minced 1 red bell pepper diced 1 cup baby spinach roughly chopped (optional)
  • Pantry: 2 tablespoons olive oil 1 1/2 cups (300 g) orzo pasta 2 1/2 cups (600 ml) low sodium chicken broth 1 cup (240 ml) heavy cream 1/2 cup (120 ml) milk
  • Spices & Seasonings: 1 tablespoon Cajun seasoning (store bought or homemade) 1/2 teaspoon smoked paprika 1/2 teaspoon salt or to taste 1/4 teaspoon freshly ground black pepper Pinch of cayenne pepper (optional for extra heat)
  • Cheeses: 3/4 cup (75 g) freshly grated Parmesan cheese
  • Garnish: Chopped fresh parsley Extra Parmesan cheese

Instructions

Step 1:
Season the chicken pieces with half of the Cajun seasoning salt and pepper.
Step 2:
In a large deep skillet or Dutch oven heat olive oil over medium high heat Add the chicken and sauté until browned and just cooked through about 5 6 minutes Remove chicken to a plate and set aside.
Step 3:
In the same pot add onion and bell pepper Sauté for 3 minutes until softened Add garlic and cook for 1 minute more.
Step 4:
Stir in the orzo smoked paprika remaining Cajun seasoning and cayenne pepper Toast the orzo for 1 minute stirring frequently.
Step 5:
Pour in the chicken broth heavy cream and milk Stir well scraping any browned bits from the bottom.
Step 6:
Bring to a gentle boil then reduce heat to medium low Cover and simmer for 10 12 minutes stirring occasionally until orzo is tender and most liquid is absorbed.
Step 7:
Return the chicken to the pot along with spinach (if using) Stir in Parmesan cheese until melted and creamy.
Step 8:
Taste and adjust seasoning If sauce is too thick add a splash more milk or broth.
Step 9:
Serve hot garnished with parsley and extra Parmesan.
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This dish quickly became a family favorite, perfect for cozy dinners and gatherings.

Notes

Additional vegetables like mushrooms or peas can be added for extra nutrition Serve with crusty bread or a green salad for a complete meal.

Required Tools

Large deep skillet or Dutch oven with lid Cutting board and knife Wooden spoon or spatula Measuring cups and spoons Grater (for Parmesan)

Allergen Information

Contains Dairy (cream milk Parmesan) Wheat (orzo) Possible Celery (in broth) Check Cajun seasoning and broth labels for hidden allergens.

This photo shows a bubbling One-Pot Cajun Chicken Alfredo Orzo with a sprinkle of fresh parsley on top. Save
This photo shows a bubbling One-Pot Cajun Chicken Alfredo Orzo with a sprinkle of fresh parsley on top. | pepperplume.com

Enjoy this rich and flavorful dish that’s sure to impress your family and friends.

Recipe FAQ

How do I prevent the orzo from sticking?

Toast the orzo lightly in oil or butter before adding liquids and stir occasionally during cooking to avoid sticking.

Can I substitute the chicken with other proteins?

Yes, shrimp or smoked sausage work well and bring different flavor profiles while maintaining the dish's essence.

What gives this dish its creamy texture?

The combination of heavy cream, milk, and Parmesan cheese creates a rich, velvety sauce that coats the orzo and chicken.

Is it possible to add vegetables to this dish?

Absolutely. Spinach, peas, mushrooms, or bell peppers can be incorporated for added flavor and nutrition.

How spicy is this dish?

The Cajun seasoning and cayenne pepper introduce moderate heat, which can be adjusted or omitted based on preference.

What type of pan is best for cooking this meal?

A large deep skillet or Dutch oven with a lid ensures even cooking and enough space for stirring all ingredients together.

Cajun Chicken Alfredo Orzo

Creamy, spicy chicken with orzo and Alfredo sauce, cooked all in one pot for ease.

Prep duration
15 min
Cook duration
25 min
Complete duration
40 min
Created by Isabella Flores


Complexity Easy

Heritage American, Cajun-Inspired

Output 4 Portions

Diet considerations None specified

Components

Proteins

01 2 large boneless, skinless chicken breasts (approximately 16 ounces), cut into bite-sized pieces

Vegetables

01 1 small yellow onion, finely chopped
02 3 cloves garlic, minced
03 1 red bell pepper, diced
04 1 cup baby spinach, roughly chopped (optional)

Pantry

01 2 tablespoons olive oil
02 1 1/2 cups orzo pasta (about 10.5 ounces)
03 2 1/2 cups low-sodium chicken broth (20 fluid ounces)
04 1 cup heavy cream (8 fluid ounces)
05 1/2 cup milk (4 fluid ounces)

Spices & Seasonings

01 1 tablespoon Cajun seasoning
02 1/2 teaspoon smoked paprika
03 1/2 teaspoon salt, or to taste
04 1/4 teaspoon freshly ground black pepper
05 Pinch of cayenne pepper (optional)

Cheeses

01 3/4 cup freshly grated Parmesan cheese (approximately 2.5 ounces)

Garnish

01 Chopped fresh parsley
02 Extra Parmesan cheese

Directions

Phase 01

Season chicken: Combine chicken pieces with half the Cajun seasoning, salt, and black pepper; mix thoroughly to coat evenly.

Phase 02

Sauté chicken: Heat olive oil in a large, deep skillet or Dutch oven over medium-high heat. Add chicken and cook until browned and just cooked through, about 5 to 6 minutes. Remove chicken from pan and set aside.

Phase 03

Cook vegetables: In the same pan, add chopped onion and diced bell pepper. Sauté for 3 minutes until softened, then stir in minced garlic and cook for 1 more minute.

Phase 04

Toast orzo and spices: Add orzo pasta, smoked paprika, remaining Cajun seasoning, and cayenne pepper to the pan. Toast for 1 minute, stirring frequently to prevent sticking.

Phase 05

Add liquids and simmer: Pour in chicken broth, heavy cream, and milk. Stir well, scraping the bottom to release any browned bits. Bring to a gentle boil, then reduce heat to medium-low, cover, and simmer for 10 to 12 minutes, stirring occasionally, until orzo is tender and most liquid is absorbed.

Phase 06

Combine chicken and spinach: Return cooked chicken and optional spinach to the pot. Stir in Parmesan cheese until melted and sauce reaches a creamy consistency.

Phase 07

Adjust seasoning and serve: Taste and adjust seasoning if necessary. If sauce is too thick, add a splash of milk or broth. Serve hot, garnished with chopped parsley and additional Parmesan cheese.

Necessary tools

  • Large, deep skillet or Dutch oven with lid
  • Cutting board and knife
  • Wooden spoon or spatula
  • Measuring cups and spoons
  • Grater for Parmesan cheese

Allergy details

Review each ingredient for potential allergens and seek professional health advice if you're uncertain.
  • Contains dairy (cream, milk, Parmesan), wheat (orzo); may contain celery depending on broth and seasoning used.

Nutrient breakdown (per portion)

These values are estimates only and shouldn't replace professional medical guidance.
  • Energy: 570
  • Fats: 27 g
  • Carbohydrates: 48 g
  • Proteins: 37 g