One-Pot Cajun Chicken Alfredo

Featured in: Spicy Entrées

This dish brings together tender chicken, al dente orzo, and a creamy, spicy Cajun sauce all in one pot. Combining sautéed chicken with a fragrant blend of garlic, onion, and Cajun spices, it's simmered in a rich sauce of cream and Parmesan for a luscious finish. Ready in just 30 minutes, it’s an ideal option for busy evenings when comfort and bold flavors are needed on the table.

Optional substitutions like shrimp or Andouille sausage add variety, and garnishing with fresh parsley brightens the plate. This meal pairs well with crusty bread or a green salad, making it both hearty and balanced.

Updated on Sun, 23 Nov 2025 08:45:00 GMT
One-Pot Cajun Chicken Alfredo Orzo, a creamy skillet full of tender chicken and flavorful pasta. Save
One-Pot Cajun Chicken Alfredo Orzo, a creamy skillet full of tender chicken and flavorful pasta. | pepperplume.com

A quick and creamy one-pot meal that blends tender chicken, al dente orzo, and a zesty Cajun Alfredo sauce. Perfect for busy weeknights, this dish delivers bold flavors and comforting richness in just 30 minutes.

This dish has become a favorite for weeknight dinners because of its ease and flavor balance.

Ingredients

  • Chicken: 1 lb (450 g) chicken breast, diced (substitute with shrimp or Andouille sausage if desired), salt and black pepper to taste
  • Spice Blend: 1 tbsp Cajun seasoning (adjust for spice preference), 1 tsp smoked paprika (regular paprika can be used), 1/4 tsp red pepper flakes (optional for extra heat)
  • Base: 2 tbsp olive oil, 2 tbsp butter, 1 medium onion chopped (yellow or sweet preferred), 3 cloves garlic minced
  • Pasta: 1 cup (190 g) orzo pasta (substitute with other small pasta if needed)
  • Sauce: 2 cups (480 ml) low sodium chicken broth, 1 cup (240 ml) heavy cream (or half and half for a lighter version), 1 cup (90 g) Parmesan cheese freshly grated
  • Garnish: 1 tbsp fresh parsley chopped

Instructions

Step 1:
Heat olive oil and butter in a large skillet over medium high heat. Add diced chicken, season with salt and pepper, and sear for 3 4 minutes until golden brown. Remove chicken and set aside.
Step 2:
In the same skillet, add chopped onion and sauté for 2 3 minutes until translucent. Stir in minced garlic and cook for 1 minute until fragrant.
Step 3:
Add orzo pasta to the skillet, stirring to combine. Toast for 1 2 minutes until lightly golden.
Step 4:
Pour in chicken broth and sprinkle in Cajun seasoning, smoked paprika, and red pepper flakes. Stir well, bring to a boil, then reduce heat to low. Cover and simmer for 10 12 minutes, stirring occasionally, until orzo is al dente and most of the liquid is absorbed.
Step 5:
Remove skillet from heat. Gradually stir in heavy cream and Parmesan cheese until the sauce is creamy and smooth.
Step 6:
Return the cooked chicken to the skillet and stir to combine. Heat through for 1 minute. Taste and adjust seasoning as needed.
Step 7:
Garnish with fresh parsley before serving.
Golden chicken pieces nestled in a rich Cajun Alfredo sauce with perfectly cooked orzo in this one-pot meal. Save
Golden chicken pieces nestled in a rich Cajun Alfredo sauce with perfectly cooked orzo in this one-pot meal. | pepperplume.com

This recipe always brings the family around the table smiling, sharing stories of the day while enjoying the meal.

Notes

Add bell peppers or spinach for extra vegetables and color. Serve with crusty bread or a green salad. Pairs well with a chilled Sauvignon Blanc or light lager.

Required Tools

Large skillet with lid, wooden spoon or spatula, chefs knife, cutting board, measuring cups and spoons, grater for Parmesan.

Allergen Information

Contains dairy (butter, cream, Parmesan cheese) and gluten (orzo pasta). May contain traces of other allergens always check ingredient labels if sensitivity is a concern.

Imagine a steaming bowl of one-pot Cajun Chicken Alfredo Orzo, garnished with fresh parsley and ready to eat. Save
Imagine a steaming bowl of one-pot Cajun Chicken Alfredo Orzo, garnished with fresh parsley and ready to eat. | pepperplume.com

This rich and simple dish is sure to become a staple for busy weeknights with its comforting creamy sauce and savory Cajun kick.

Recipe FAQ

Can I substitute the chicken with other proteins?

Yes, shrimp or Andouille sausage make great alternatives and can be used with slight adjustments to cooking time.

Is it possible to use a different pasta than orzo?

Absolutely, other small pasta shapes work well; just adjust cook time accordingly for al dente texture.

How can I reduce the richness of the sauce?

Using half and half instead of heavy cream and slightly reducing the cheese will lighten the sauce without sacrificing flavor.

What level of spiciness does this dish have?

The Cajun seasoning and optional red pepper flakes add moderate heat, which you can adjust to suit your preference.

What side dishes complement this meal best?

Serve with crusty bread or a fresh green salad to balance the creamy, bold flavors.

Can I prepare this dish all in one pan?

Yes, the recipe is designed as a one-pot dish to simplify cooking and cleanup.

One-Pot Cajun Chicken Alfredo

A creamy, spicy chicken and orzo dish with a zesty Cajun twist, perfect for quick, flavorful meals.

Prep duration
10 min
Cook duration
20 min
Complete duration
30 min
Created by Isabella Flores


Complexity Easy

Heritage Cajun

Output 4 Portions

Diet considerations None specified

Components

Chicken

01 1 lb diced chicken breast
02 Salt, to taste
03 Black pepper, to taste

Spice Blend

01 1 tbsp Cajun seasoning
02 1 tsp smoked paprika
03 1/4 tsp red pepper flakes (optional)

Base

01 2 tbsp olive oil
02 2 tbsp butter
03 1 medium onion, chopped
04 3 cloves garlic, minced

Pasta

01 1 cup orzo pasta

Sauce

01 2 cups low-sodium chicken broth
02 1 cup heavy cream
03 1 cup freshly grated Parmesan cheese

Garnish

01 1 tbsp fresh parsley, chopped

Directions

Phase 01

Sear Chicken: Heat olive oil and butter in a large skillet over medium-high heat. Add diced chicken, season with salt and pepper, and cook until golden brown, about 3 to 4 minutes. Remove chicken and set aside.

Phase 02

Sauté Aromatics: In the same skillet, add chopped onion and cook for 2 to 3 minutes until translucent. Stir in minced garlic and cook for an additional minute until fragrant.

Phase 03

Toast Orzo: Add orzo pasta to the skillet and stir to combine. Toast for 1 to 2 minutes until lightly golden.

Phase 04

Simmer Pasta with Spices: Pour in chicken broth and add Cajun seasoning, smoked paprika, and red pepper flakes. Stir well and bring to a boil. Reduce heat to low, cover, and simmer for 10 to 12 minutes, stirring occasionally until orzo is al dente and liquid is mostly absorbed.

Phase 05

Incorporate Cream and Cheese: Remove skillet from heat and slowly stir in heavy cream and Parmesan cheese until the sauce is smooth and creamy.

Phase 06

Combine Chicken and Heat Through: Return cooked chicken to the skillet and mix well. Heat through for 1 minute and adjust seasoning if necessary.

Phase 07

Garnish and Serve: Sprinkle chopped fresh parsley over the dish before serving.

Necessary tools

  • Large skillet with lid
  • Wooden spoon or spatula
  • Chef’s knife
  • Cutting board
  • Measuring cups and spoons
  • Grater

Allergy details

Review each ingredient for potential allergens and seek professional health advice if you're uncertain.
  • Contains dairy and gluten

Nutrient breakdown (per portion)

These values are estimates only and shouldn't replace professional medical guidance.
  • Energy: 560
  • Fats: 28 g
  • Carbohydrates: 45 g
  • Proteins: 35 g